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Prenatal Exposure to Low Levels of Androgen Accelerates Female Puberty Onset and Reproductive Senescence in Mice

Sex steroid hormone production and feedback mechanisms are critical components of the hypothalamic-pituitary-gonadal (HPG) axis and regulate fetal development, puberty, fertility, and menopause. In female mammals, developmental exposure to excess androgens alters the development of the HPG axis and...

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Detalhes bibliográficos
Main Authors: Witham, Emily A., Meadows, Jason D., Shojaei, Shadi, Kauffman, Alexander S., Mellon, Pamela L.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423623/
https://ncbi.nlm.nih.gov/pubmed/22778229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1283
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