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Interferon induction by mismatched analogues of polyinosinic acid . polycytidylic acid [(Ix,U)n.(C)n].

Interruption of the (I)n strand of (I)n.(C)n by unpaired bases [(U)] yielded mismatched analogues, (Ix,U)n.(C)n which were still effective as inducers of interferon, provided the I:U ratio (x) was equal or greater than 10. In highly sensitive interferon-induction systems such as primary rabbit kidne...

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Main Authors: De Clercq, E, Huang, G F, Bhooshan, B, Ledley, G, Torrence, P F
Formato: Artigo
Idioma:Inglês
Publicado: 1979
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC342362/
https://ncbi.nlm.nih.gov/pubmed/537917
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