Estrogenic Compounds Are Not Always Cardioprotective and Can Be Lethal in Males with Genetic Heart Disease

Hypertrophic cardiomyopathy (HCM) is more severe in male than female mice eating a soy-based diet. We sought to determine whether the detrimental effects are mediated by the phytoestrogens present in soy, the mechanism by which phytoestrogens act, and to test whether estrogen modulates the sexually...

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Main Authors: Haines, Christopher D., Harvey, Pamela A., Luczak, Elizabeth D., Barthel, Kristen K. B., Konhilas, John P., Watson, Peter A., Stauffer, Brian L., Leinwand, Leslie A.
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2012
Assuntos:
Renal-Cardiac-Vascular
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423614/
https://ncbi.nlm.nih.gov/pubmed/22778230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1391
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