Estrogenic Compounds Are Not Always Cardioprotective and Can Be Lethal in Males with Genetic Heart Disease

Hypertrophic cardiomyopathy (HCM) is more severe in male than female mice eating a soy-based diet. We sought to determine whether the detrimental effects are mediated by the phytoestrogens present in soy, the mechanism by which phytoestrogens act, and to test whether estrogen modulates the sexually...

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Hlavní autoři: Haines, Christopher D., Harvey, Pamela A., Luczak, Elizabeth D., Barthel, Kristen K. B., Konhilas, John P., Watson, Peter A., Stauffer, Brian L., Leinwand, Leslie A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2012
Témata:
Renal-Cardiac-Vascular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423614/
https://ncbi.nlm.nih.gov/pubmed/22778230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1391
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