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TLR4, 5, and 9 Agonists Inhibit Murine Airway Invariant Natural Killer T Cells in an IL-12-Dependent Manner

PURPOSE: Invariant natural killer T (iNKT) cells may play an important role in the pathogenesis of asthma in mice and humans. Thus, an agent that modulates the function of iNKT cells may have therapeutic potential to control asthma. We hypothesized that lipopolysaccharide (LPS)-, flagellin-, or CpG-...

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Bibliografske podrobnosti
Main Authors: Shim, Jae-Uoong, Rhee, Joon-Haeng, Koh, Young-Il
Format: Artigo
Jezik:Inglês
Izdano: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423604/
https://ncbi.nlm.nih.gov/pubmed/22950036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4168/aair.2012.4.5.295
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