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The use of barium salts of protected deoxyribonucleoside-3' p-chlorophenyl phosphates for construction of oligonucleotides by the phosphotriester method: high-yield synthesis of dinucleotide blocks.

A new experimental approach to the synthesis of polydeoxyribonucleotides via the phosphotriester method involves construction of oligonucleotide blocks by direct use of the easily prepared barium salts of O5',N-protected deoxyribonucleoside-3' p-chlorophenyl phosphates as the key monomers in condens...

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Publicat a:Nucleic Acids Res
Autors principals: Gough, G R, Collier, K J, Weith, H L, Gilham, P T
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1979
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC342359/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/537916/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/7.7.1955
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