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CD8(+) T Cell Clones Specific for the 5T4 Antigen Target Renal Cell Carcinoma Tumor-Initiating Cells in a Murine Xenograft Model

The tumor antigen 5T4 is frequently expressed at high levels on renal cell carcinoma (RCC) and other epithelial carcinomas. Surveys of normal tissues demonstrate abundant 5T4 expression on placental trophoblast cells with limited expression elsewhere. 5T4 is the target for a therapeutic cancer vacci...

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Autors principals: Tykodi, Scott S., Satoh, Shoko, Deming, Janise D., Chou, Jeffrey, Harrop, Richard, Warren, Edus H.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423552/
https://ncbi.nlm.nih.gov/pubmed/22892449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e318261d630
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