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Generation of DNA-damaging reactive oxygen species via the autoxidation of hydrogen sulfide under physiologically-relevant conditions: chemistry relevant to both the genotoxic and cell signaling properties of H(2)S

Hydrogen sulfide (H(2)S) has long been known for its toxic properties; however, in recent years, evidence has emerged that this small, gaseous molecule may serve as an endogenous cell-signaling agent. Though perhaps surprising in light of its potential role as an endogenous signaling agent, a number...

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Detalhes bibliográficos
Main Authors: Hoffman, Marjorie, Rajapakse, Anuruddha, Shen, Xiulong, Gates, Kent S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423486/
https://ncbi.nlm.nih.gov/pubmed/22621314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300066z
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