Kinetic stability as a mechanism for protease longevity
The folding of the extracellular serine protease, α-lytic protease (αLP; EC 3.4.21.12) reveals a novel mechanism for stability that appears to lead to a longer functional lifetime for the protease. For αLP, stability is based not on thermodynamics, but on kinetics. Whereas this has required the coev...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34233/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500115/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.20.11008 |
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