Effects of palmitoylation of Cys(415) in helix 8 of the CB(1) cannabinoid receptor on membrane localization and signalling

BACKGROUND AND PURPOSE: The CB(1) cannabinoid receptor is regulated by its association with membrane microdomains such as lipid rafts. Here, we investigated the role of palmitoylation of the CB(1) receptor by analysing the functional consequences of site-specific mutation of Cys(415), the likely sit...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Oddi, Sergio, Dainese, Enrico, Sandiford, Simone, Fezza, Filomena, Lanuti, Mirko, Chiurchiù, Valerio, Totaro, Antonio, Catanzaro, Giuseppina, Barcaroli, Daniela, De Laurenzi, Vincenzo, Centonze, Diego, Mukhopadhyay, Somnath, Selent, Jana, Howlett, Allyn C, Maccarrone, Mauro
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Themed Section: Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423250/
https://ncbi.nlm.nih.gov/pubmed/21895628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01658.x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados