p120-Catenin prevents neutrophil transmigration independently of RhoA inhibition by impairing Src dependent VE-cadherin phosphorylation

Leukocyte transendothelial migration (TEM) is regulated by several signaling pathways including Src family kinases (SFK) and the small RhoGTPases. Previous studies have shown that vascular endothelial-cadherin (VE-cad) forms a complex with β-,γ-, and p120-catenins and this complex disassociates to f...

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Bibliographic Details
Main Authors: Alcaide, Pilar, Martinelli, Roberta, Newton, Gail, Williams, Marcie R., Adam, Alejandro, Vincent, Peter A., Luscinskas, Francis W.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422989/
https://ncbi.nlm.nih.gov/pubmed/22648953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00126.2012
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