Oxymatrine liposome attenuates hepatic fibrosis via targeting hepatic stellate cells

AIM: To investigate the potential mechanism of Arg-Gly-Asp (RGD) peptide-labeled liposome loading oxymatrine (OM) therapy in CCl(4)-induced hepatic fibrosis in rats. METHODS: We constructed a rat model of CCl(4)-induced hepatic fibrosis and treated the rats with different formulations of OM. To eval...

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Main Authors: Chai, Ning-Li, Fu, Qiang, Shi, Hui, Cai, Chang-Hao, Wan, Jun, Xu, Shi-Ping, Wu, Ben-Yan
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Co., Limited 2012
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Brief Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422802/
https://ncbi.nlm.nih.gov/pubmed/22919254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i31.4199
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