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Increased binding of ethidium bromide to polynucleotide duplexes containing mismatched bases.
The binding of the intercalating dye ethidium bromide to a series of synthetic polynucleotide duplexes containing varying concentrations of mismatched bases has been measured by fluorescence titration. The dye binds more strongly to duplexes with mismatches, the estimated increase in affinity being...
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| Главные авторы: | , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1979
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC342278/ https://ncbi.nlm.nih.gov/pubmed/503848 |
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