Rapid tumoritropic accumulation of systemically injected plateloid particles and their biodistribution

Nanoparticles for cancer therapy and imaging are designed to accumulate in the diseased tissue by exploiting the Enhanced Permeability and Retention (EPR) effect. This limits their size to about 100 nm. Here, using intravital microscopy and elemental analysis, we compare the in vivo localization of...

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Detalhes bibliográficos
Main Authors: van de Ven, Anne L., Kim, Pilhan, Haley, O’Hara, Fakhoury, Jean R., Adriani, Giulia, Schmulen, Jeffrey, Moloney, Padraig, Hussain, Fazle, Ferrari, Mauro, Liu, Xuewu, Yun, Seok-Hyun, Decuzzi, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422657/
https://ncbi.nlm.nih.gov/pubmed/22062689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.10.021
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