Rapid tumoritropic accumulation of systemically injected plateloid particles and their biodistribution

Nanoparticles for cancer therapy and imaging are designed to accumulate in the diseased tissue by exploiting the Enhanced Permeability and Retention (EPR) effect. This limits their size to about 100 nm. Here, using intravital microscopy and elemental analysis, we compare the in vivo localization of...

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Hlavní autoři: van de Ven, Anne L., Kim, Pilhan, Haley, O’Hara, Fakhoury, Jean R., Adriani, Giulia, Schmulen, Jeffrey, Moloney, Padraig, Hussain, Fazle, Ferrari, Mauro, Liu, Xuewu, Yun, Seok-Hyun, Decuzzi, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422657/
https://ncbi.nlm.nih.gov/pubmed/22062689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.10.021
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