Rapid tumoritropic accumulation of systemically injected plateloid particles and their biodistribution

Nanoparticles for cancer therapy and imaging are designed to accumulate in the diseased tissue by exploiting the Enhanced Permeability and Retention (EPR) effect. This limits their size to about 100 nm. Here, using intravital microscopy and elemental analysis, we compare the in vivo localization of...

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Bibliografiska uppgifter
Huvudupphovsmän: van de Ven, Anne L., Kim, Pilhan, Haley, O’Hara, Fakhoury, Jean R., Adriani, Giulia, Schmulen, Jeffrey, Moloney, Padraig, Hussain, Fazle, Ferrari, Mauro, Liu, Xuewu, Yun, Seok-Hyun, Decuzzi, Paolo
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422657/
https://ncbi.nlm.nih.gov/pubmed/22062689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.10.021
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