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Natural-host animal models indicate functional interchangeability between the filamentous haemagglutinins of Bordetella pertussis and Bordetella bronchiseptica and reveal a role for the mature C-terminal domain, but not the RGD motif, during infection

Bacteria of the Bordetella genus cause respiratory tract infections. Both broad host range (e.g. Bordetella bronchiseptica) and human-adapted (e.g. Bordetella pertussis) strains produce a surface-exposed and secreted protein called filamentous haemagglutinin (FHA) that functions in adherence and imm...

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Detalhes bibliográficos
Main Authors: Julio, Steven M., Inatsuka, Carol S., Mazar, Joseph, Dieterich, Christine, Relman, David A., Cotter, Peggy A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422645/
https://ncbi.nlm.nih.gov/pubmed/19220744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2009.06623.x
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