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Yohimbine Depresses Excitatory Transmission in BNST and Impairs Extinction of Cocaine Place Preference Through Orexin-Dependent, Norepinephrine-Independent Processes

The alpha2 adrenergic receptor (α(2)-AR) antagonist yohimbine is a widely used tool for the study of anxiogenesis and stress-induced drug-seeking behavior. We previously demonstrated that yohimbine paradoxically depresses excitatory transmission in the bed nucleus of the stria terminalis (BNST), a r...

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Hlavní autoři: Conrad, Kelly L, Davis, Adeola R, Silberman, Yuval, Sheffler, Douglas J, Shields, Angela D, Saleh, Sam A, Sen, Namita, Matthies, Heinrich JG, Javitch, Jonathan A, Lindsley, Craig W, Winder, Danny G
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422490/
https://ncbi.nlm.nih.gov/pubmed/22617356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.76
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