Prevention of the Phencyclidine-Induced Impairment in Novel Object Recognition in Female Rats by Co-Administration of Lurasidone or Tandospirone, a 5-HT(1A) Partial Agonist

Hypoglutamatergic function may contribute to cognitive impairment in schizophrenia (CIS). Subchronic treatment with the N-methyl-D-aspartate receptor antagonist, phencyclidine (PCP), induces enduring deficits in novel object recognition (NOR) in rodents. Acute treatment with atypical antipsychotic d...

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Main Authors: Horiguchi, Masakuni, Hannaway, Kayleen E, Adelekun, Adesewa E, Jayathilake, Karu, Meltzer, Herbert Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422483/
https://ncbi.nlm.nih.gov/pubmed/22739469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.64
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