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Safety in glomerular numbers
A low nephron number is, according to Brenner’s hyperfiltration hypothesis, associated with hypertension, glomerular damage and proteinuria, and starts a vicious cycle that ends in renal failure over the long term. Nephron endowment is set during foetal life, and there is no formation of nephrons af...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer-Verlag
2012
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3422453/ https://ncbi.nlm.nih.gov/pubmed/22532329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-012-2169-x |
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