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DNAse footprinting: a simple method for the detection of protein-DNA binding specificity.

A method for studying the sequence-specific binding of proteins to DBA is described. The technique is a simple conjoining of the Maxam-Gilbert DNA-sequencing method and the technique of DNAase-protected fragment isolation. Fragments of a 5' end-labelled, double-stranded DNA segment, partially d...

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Bibliographic Details
Main Authors: Galas, D J, Schmitz, A
Format: Artigo
Language:Inglês
Published: 1978
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC342238/
https://ncbi.nlm.nih.gov/pubmed/212715
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