Chemical synthesis of 5'-pyrophosphate and triphosphate derivatives of 3'-5' ApA, ApG, GpA and GpG. CD study of the effect of 5'-phosphate groups on the conformation of 3'-5' GpG.

A simple, two-step method is described for the synthesis of the 5'-pyro- and triphosphate derivatives of 3'-5' ApA, ApG, GpA and GpG. The readily accessible 2'(3')-5' ApA, ApG, GpA and GpG were converted in one step to the corresponding 5'-phosphoramidate derivativ...

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Hauptverfasser: Tomasz, J, Simoncsits, A, Kajtár, M, Krug, R M, Shatkin, A J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1978
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC342217/
https://ncbi.nlm.nih.gov/pubmed/211490
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