Recombinant human decorin suppresses liver HepG2 carcinoma cells by p21 upregulation

BACKGROUND: Decorin is a multifunctional molecule of the extracellular matrix and impedes different kinds of tumor cell growth, but the role and molecular mechanism by which decorin inhibits HepG2 cells is not fully understood. Our objective was to construct recombinant human decorin (pcDNA3.1-DCN)...

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Bibliografski detalji
Glavni autori: Zhang, Yucheng, Wang, Yali, Du, Zhenwu, Wang, Qian, Wu, Mei, Wang, Xiaofeng, Wang, Lingling, Cao, Linlin, Hamid, Abdu Selim, Zhang, Guizhen
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2012
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422087/
https://ncbi.nlm.nih.gov/pubmed/22927763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S32918
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