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Multiple Roles for the Ess1 Prolyl Isomerase in the RNA Polymerase II Transcription Cycle
The Ess1 prolyl isomerase in Saccharomyces cerevisiae regulates RNA polymerase II (pol II) by isomerizing peptide bonds within the pol II carboxy-terminal domain (CTD) heptapeptide repeat (YSPTSPS). Ess1 preferentially targets the Ser5-Pro6 bond when Ser5 is phosphorylated. Conformational changes in...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3422015/ https://ncbi.nlm.nih.gov/pubmed/22778132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00672-12 |
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