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Multiple Roles for the Ess1 Prolyl Isomerase in the RNA Polymerase II Transcription Cycle

The Ess1 prolyl isomerase in Saccharomyces cerevisiae regulates RNA polymerase II (pol II) by isomerizing peptide bonds within the pol II carboxy-terminal domain (CTD) heptapeptide repeat (YSPTSPS). Ess1 preferentially targets the Ser5-Pro6 bond when Ser5 is phosphorylated. Conformational changes in...

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Bibliografski detalji
Glavni autori: Ma, Zhuo, Atencio, David, Barnes, Cassandra, DeFiglio, Holland, Hanes, Steven D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422015/
https://ncbi.nlm.nih.gov/pubmed/22778132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00672-12
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