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Emergence of High-Level Mupirocin Resistance in Coagulase-Negative Staphylococci Associated with Increased Short-Term Mupirocin Use

In our hospital, mupirocin has increasingly been used for peri-operative decolonization of Staphylococcus aureus. The target for mupirocin is isoleucyl tRNA synthetase (ileS). High-level resistance to mupirocin is conferred by acquisition of plasmids expressing a distinct ileS gene (ileS2). Here we...

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Detalhes bibliográficos
Main Authors: Bathoorn, Erik, Hetem, David J., Alphenaar, Jeriela, Kusters, Johannes G., Bonten, Marc J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421826/
https://ncbi.nlm.nih.gov/pubmed/22760047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00302-12
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