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The degradation of DNA by hydrazine: identification of 3-ureidopyrazole as a product of the hydrazinolysis of deoxycytidylic acid residues.
The reaction of hydrazine with the cytosine residues of DNA yields 3-ureidopyrazole, in approximately 50% yield, in addition to the expected 3-aminopyrazole. This product has been identified by ultraviolet, infrared, nuclear magnetic resonance and mass spectroscopy. A product of the reaction of hydr...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1978
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC342178/ https://ncbi.nlm.nih.gov/pubmed/353742 |
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