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The degradation of DNA by hydrazine: identification of 3-ureidopyrazole as a product of the hydrazinolysis of deoxycytidylic acid residues.

The reaction of hydrazine with the cytosine residues of DNA yields 3-ureidopyrazole, in approximately 50% yield, in addition to the expected 3-aminopyrazole. This product has been identified by ultraviolet, infrared, nuclear magnetic resonance and mass spectroscopy. A product of the reaction of hydr...

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Detalhes bibliográficos
Main Authors: Cashmore, A R, Petersen, G B
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC342178/
https://ncbi.nlm.nih.gov/pubmed/353742
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