Structural Variability of the Herpes Simplex Virus 1 Genome In Vitro and In Vivo

Herpes simplex virus 1 (HSV-1) is a human pathogen that leads to recurrent facial-oral lesions. Its 152-kb genome is organized in two covalently linked segments, each composed of a unique sequence flanked by inverted repeats. Replication of the HSV-1 genome produces concatemeric molecules in which h...

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Autores principales: Mahiet, Charlotte, Ergani, Ayla, Huot, Nicolas, Alende, Nicolas, Azough, Ahmed, Salvaire, Fabrice, Bensimon, Aaron, Conseiller, Emmanuel, Wain-Hobson, Simon, Labetoulle, Marc, Barradeau, Sébastien
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421737/
https://ncbi.nlm.nih.gov/pubmed/22674981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00223-12
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