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Marek's Disease Viral Interleukin-8 Promotes Lymphoma Formation through Targeted Recruitment of B Cells and CD4(+) CD25(+) T Cells

Marek's disease virus (MDV) is a cell-associated and highly oncogenic alphaherpesvirus that infects chickens. During lytic and latent MDV infection, a CXC chemokine termed viral interleukin-8 (vIL-8) is expressed. Deletion of the entire vIL-8 open reading frame (ORF) was shown to severely impai...

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Detalhes bibliográficos
Main Authors: Engel, Annemarie T., Selvaraj, Ramesh K., Kamil, Jeremy P., Osterrieder, Nikolaus, Kaufer, Benedikt B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421702/
https://ncbi.nlm.nih.gov/pubmed/22647701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00556-12
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