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Orthobunyavirus Entry into Neurons and Other Mammalian Cells Occurs via Clathrin-Mediated Endocytosis and Requires Trafficking into Early Endosomes

La Crosse virus (LACV) is a leading cause of pediatric encephalitis and aseptic meningitis in the midwestern and southern United States, where it is considered an emerging human pathogen. No specific therapies or vaccines are available for LACV or any other orthobunyaviruses. Inhibition of LACV entr...

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Detalhes bibliográficos
Main Authors: Hollidge, Bradley S., Nedelsky, Natalia B., Salzano, Mary-Virginia, Fraser, Jonathan W., González-Scarano, Francisco, Soldan, Samantha S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421672/
https://ncbi.nlm.nih.gov/pubmed/22623766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00140-12
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