Orthobunyavirus Entry into Neurons and Other Mammalian Cells Occurs via Clathrin-Mediated Endocytosis and Requires Trafficking into Early Endosomes

La Crosse virus (LACV) is a leading cause of pediatric encephalitis and aseptic meningitis in the midwestern and southern United States, where it is considered an emerging human pathogen. No specific therapies or vaccines are available for LACV or any other orthobunyaviruses. Inhibition of LACV entr...

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Hlavní autoři: Hollidge, Bradley S., Nedelsky, Natalia B., Salzano, Mary-Virginia, Fraser, Jonathan W., González-Scarano, Francisco, Soldan, Samantha S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421672/
https://ncbi.nlm.nih.gov/pubmed/22623766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00140-12
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