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cis-Acting Determinants of 7SL RNA Packaging by HIV-1

The host noncoding RNA 7SL is highly enriched in the virions of retroviruses. We examined the regions of 7SL that mediate packaging by HIV-1. Both the Alu domain and the S domain were sufficient to mediate specific packaging when expressed separately as truncations of 7SL. However, while the Alu dom...

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Bibliographic Details
Main Authors: Keene, Sarra E., Telesnitsky, Alice
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421668/
https://ncbi.nlm.nih.gov/pubmed/22593161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00856-12
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