Expression of Human Endogenous Retrovirus Type K (HML-2) Is Activated by the Tat Protein of HIV-1

Human endogenous retroviruses (HERVs) make up 8% of the human genome. The expression of HERV-K (HML-2), the family of HERVs that most recently entered the genome, is tightly regulated but becomes markedly increased after infection with HIV-1. To better understand the mechanisms involved in this acti...

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Detalhes bibliográficos
Main Authors: Gonzalez-Hernandez, Marta J., Swanson, Michael D., Contreras-Galindo, Rafael, Cookinham, Sarah, King, Steven R., Noel, Richard J., Kaplan, Mark H., Markovitz, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421662/
https://ncbi.nlm.nih.gov/pubmed/22593154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.07215-11
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