Poly(A)-Binding Protein Facilitates Translation of an Uncapped/Nonpolyadenylated Viral RNA by Binding to the 3′ Untranslated Region

Viruses employ an alternative translation mechanism to exploit cellular resources at the expense of host mRNAs and to allow preferential translation. Plant RNA viruses often lack both a 5′ cap and a 3′ poly(A) tail in their genomic RNAs. Instead, cap-independent translation enhancer elements (CITEs)...

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Auteurs principaux: Iwakawa, Hiro-oki, Tajima, Yuri, Taniguchi, Takako, Kaido, Masanori, Mise, Kazuyuki, Tomari, Yukihide, Taniguchi, Hisaaki, Okuno, Tetsuro
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Genome Replication and Regulation of Viral Gene Expression
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421650/
https://ncbi.nlm.nih.gov/pubmed/22593149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00538-12
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