Poly(A)-Binding Protein Facilitates Translation of an Uncapped/Nonpolyadenylated Viral RNA by Binding to the 3′ Untranslated Region

Viruses employ an alternative translation mechanism to exploit cellular resources at the expense of host mRNAs and to allow preferential translation. Plant RNA viruses often lack both a 5′ cap and a 3′ poly(A) tail in their genomic RNAs. Instead, cap-independent translation enhancer elements (CITEs)...

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Main Authors: Iwakawa, Hiro-oki, Tajima, Yuri, Taniguchi, Takako, Kaido, Masanori, Mise, Kazuyuki, Tomari, Yukihide, Taniguchi, Hisaaki, Okuno, Tetsuro
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2012
主題:
Genome Replication and Regulation of Viral Gene Expression
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421650/
https://ncbi.nlm.nih.gov/pubmed/22593149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00538-12
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