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Resistance to a Novel Antichlamydial Compound Is Mediated through Mutations in Chlamydia trachomatis secY
A novel and quantitative high-throughput screening approach was explored as a tool for the identification of novel compounds that inhibit chlamydial growth in mammalian cells. The assay is based on accumulation of a fluorescent marker by intracellular chlamydiae. Its utility was demonstrated by scre...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3421553/ https://ncbi.nlm.nih.gov/pubmed/22644029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00356-12 |
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