From Quellung to Multiplex PCR, and Back When Needed, in Pneumococcal Serotyping

All currently available vaccines against Streptococcus pneumoniae are based on selections of the over 90 different serotypes, which underlines the importance of serotyping for surveillance and vaccine efficacy monitoring. In this study, we modified and validated a PCR-based scheme for deducing the s...

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Bibliographic Details
Main Authors: Siira, Lotta, Kaijalainen, Tarja, Lambertsen, Lotte, Nahm, Moon H., Toropainen, Maija, Virolainen, Anni
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Bacteriology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421528/
https://ncbi.nlm.nih.gov/pubmed/22692742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00689-12
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