Heterogeneity of cholinergic denervation in Parkinson's disease without dementia

Parkinson's disease (PD) is a multisystem neurodegenerative disorder. Heterogeneous clinical features may reflect heterogeneous changes in different brain regions. In contrast to the pronounced nigrostriatal denervation characteristic of PD, cholinergic changes are less marked. We investigated...

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Detalhes bibliográficos
Main Authors: Bohnen, Nicolaas I, Müller, Martijn L T M, Kotagal, Vikas, Koeppe, Robert A, Kilbourn, Michael R, Gilman, Sid, Albin, Roger L, Frey, Kirk A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421100/
https://ncbi.nlm.nih.gov/pubmed/22569194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.60
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