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NAC1 is an actin-binding protein that is essential for effective cytokinesis in cancer cells

NAC1 is a transcriptional co-repressor protein that is essential to sustain cancer cell proliferation and migration. However, the underlying molecular mechanisms of NAC1 function in cancer cells remain unknown. In this study, we show that NAC1 functions as an actin monomer binding protein. The conse...

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Main Authors: Yap, Kai Lee, Fraley, Stephanie I., Thiaville, Michelle M., Jinawath, Natini, Nakayama, Kentaro, Wang, Jianlong, Wang, Tian-Li, Wirtz, Denis, Shih, Ie-Ming
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421062/
https://ncbi.nlm.nih.gov/pubmed/22761335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0302
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