Placental Transfer of Maternally-Derived IgA Precludes the Use of Guthrie Card Eluates as a Screening Tool for Primary Immunodeficiency Diseases

There is a need for neonatal screening tools to improve the long-term clinical outcome of patients with primary immunodeficiency diseases (PID). Recently, a PCR-based screening method for both TRECs and KRECs using Guthrie card samples has been developed. However, the applicability of these excision...

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Bibliographic Details
Main Authors: Borte, Stephan, Janzi, Magdalena, Pan-Hammarström, Qiang, von Döbeln, Ulrika, Nordvall, Lennart, Winiarski, Jacek, Fasth, Anders, Hammarström, Lennart
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420892/
https://ncbi.nlm.nih.gov/pubmed/22916257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043419
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