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MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity
Instability of the nuclear genome is a hallmark of cancer and aging. MMS19 protein has been linked to maintenance of genomic integrity but the molecular basis of this connection is unknown. Here, we identify MMS19 as a member of the cytosolic iron-sulfur protein assembly (CIA) machinery. MMS19 funct...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3420340/ https://ncbi.nlm.nih.gov/pubmed/22678362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1219723 |
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