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Direct observation of kinetic traps associated with structural transformations leading to multiple pathways of S-layer assembly
The concept of a folding funnel with kinetic traps describes folding of individual proteins. Using in situ Atomic Force Microscopy to investigate S-layer assembly on mica, we show this concept is equally valid during self-assembly of proteins into extended matrices. We find the S-layer-on-mica syste...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3420203/ https://ncbi.nlm.nih.gov/pubmed/22822216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201504109 |
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