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Mitochondrial Ca(2+) uptake contributes to buffering cytoplasmic Ca(2+) peaks in cardiomyocytes

Mitochondrial ability of shaping Ca(2+) signals has been demonstrated in a large number of cell types, but it is still debated in heart cells. Here, we take advantage of the molecular identification of the mitochondrial Ca(2+) uniporter (MCU) and of unique targeted Ca(2+) probes to directly address...

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Detalhes bibliográficos
Main Authors: Drago, Ilaria, De Stefani, Diego, Rizzuto, Rosario, Pozzan, Tullio
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420165/
https://ncbi.nlm.nih.gov/pubmed/22822213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210718109
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