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Structural and Functional Characterization of RecG Helicase under Dilute and Molecular Crowding Conditions

In an ATP-dependent reaction, the Escherichia coli RecG helicase unwinds DNA junctions in vitro. We present evidence of a unique protein conformational change in the RecG helicase from an α-helix to a β-strand upon an ATP binding under dilute conditions using circular dichroism (CD) spectroscopy. In...

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Detalhes bibliográficos
Main Authors: Saxena, Sarika, Nagatoishi, Satoru, Miyoshi, Daisuke, Sugimoto, Naoki
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420092/
https://ncbi.nlm.nih.gov/pubmed/22919464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/392039
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