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Ineffectiveness of daily standard and high-dose antiviral therapy in preventing short episodes of genital HSV-2 reactivation: three randomized, open-label cross-over trials

BACKGROUND: Recent studies indicate that short subclinical episodes of herpes simplex virus type 2 (HSV-2) are the predominant form of skin and mucosal viral shedding. We evaluated whether standard or high-dose antiviral therapy reduced the frequency of such shedding. METHODS: To determine whether s...

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Detalhes bibliográficos
Main Authors: Johnston, Christine, Saracino, Misty, Kuntz, Steve, Magaret, Amalia, Selke, Stacy, Huang, Meei-li, Schiffer, Joshua T., Koelle, David M., Corey, Lawrence, Wald, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420069/
https://ncbi.nlm.nih.gov/pubmed/22225814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(11)61750-9
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