Overexpression of the M2 isoform of pyruvate kinase is an adverse prognostic factor for signet ring cell gastric cancer

AIM: To investigate M2 isoform of pyruvate kinase (PKM2) expression in gastric cancers and evaluate its potential as a prognostic biomarker and an anticancer target. METHODS: All tissue samples were derived from gastric cancer patients underwent curative gastrectomy as a primary treatment. Clinical...

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Hauptverfasser: Lim, Jae Yun, Yoon, Sun Och, Seol, So Young, Hong, Soon Won, Kim, Jong Won, Choi, Seung Ho, Cho, Jae Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Baishideng Publishing Group Co., Limited 2012
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Brief Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420001/
https://ncbi.nlm.nih.gov/pubmed/22912555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i30.4037
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