Orotate phosphoribosyl transferase mRNA expression and the response of cholangiocarcinoma to 5-fluorouracil

AIM: To determine whether expression of certain enzymes related to 5-fluorouracil (5-FU) metabolism predicts 5-FU chemosensitivity in cholangiocarcinoma (CCA). METHODS: The histoculture drug response assay (HDRA) was performed using surgically resected CCA tissues. Tumor cell viability was determine...

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Hauptverfasser: Hahnvajanawong, Chariya, Chaiyagool, Jariya, Seubwai, Wunchana, Bhudhisawasdi, Vajarabhongsa, Namwat, Nisana, Khuntikeo, Narong, Sripa, Banchob, Pugkhem, Ake, Tassaneeyakul, Wichittra
Format: Artigo
Sprache:Inglês
Veröffentlicht: Baishideng Publishing Group Co., Limited 2012
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419992/
https://ncbi.nlm.nih.gov/pubmed/22912546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i30.3955
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