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Low-density lipoprotein receptor gene transfer in hypercholesterolemic mice improves cardiac function after myocardial infarction

Left ventricular (LV) function post-myocardial infarction (MI) is adversely influenced by hypercholesterolemia independent of the severity of coronary atherosclerosis. The objective of this study was to evaluate whether lipid lowering by adenoviral low-density lipoprotein (LDL) receptor (AdLDLr) gen...

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Détails bibliographiques
Auteurs principaux: Van Craeyveld, E, Jacobs, F, Gordts, S C, De Geest, B
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419972/
https://ncbi.nlm.nih.gov/pubmed/21975462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2011.147
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