Downregulation of miR-126 induces angiogenesis and lymphangiogenesis by activation of VEGF-A in oral cancer

BACKGROUND: MicroRNA (miRNA)-126 (miR-126) is an endothelial-specific miRNA located within intron 7 of epidermal growth factor-like domain 7 (EGFL7). However, the role of miR-126 in cancer is controversial. METHODS: We examined the function of miR-126 in oral squamous cell carcinoma (OSCC) cells. Fu...

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Detalhes bibliográficos
Main Authors: Sasahira, T, Kurihara, M, Bhawal, U K, Ueda, N, Shimomoto, T, Yamamoto, K, Kirita, T, Kuniyasu, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419968/
https://ncbi.nlm.nih.gov/pubmed/22836510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.330
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