Cytokine and angiogenic factors associated with efficacy and toxicity of pazopanib in advanced soft-tissue sarcoma: an EORTC-STBSG study

BACKGROUND: Pazopanib has activity in relapsed non-adipocytic soft-tissue sarcomas (STS). A series of serum cytokines and angiogenic factors (CAFs) at baseline and changes in soluble vascular endothelial growth factor receptor-2 (sVEGFR2) or placental-derived growth factor (PlGF) levels during treat...

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Autores principales: Sleijfer, S, Gorlia, T, Lamers, C, Burger, H, Blay, J-Y, Le Cesne, A, Scurr, M, Collin, F, Pandite, L, Marreaud, S, Hohenberger, P
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2012
Materias:
Clinical Study
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419967/
https://ncbi.nlm.nih.gov/pubmed/22805326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.328
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