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Identifying the Hotspots on the Top Faces of WD40-Repeat Proteins from Their Primary Sequences by β-Bulges and DHSW Tetrads

The analysis of 36 available crystal structures of WD40 repeat proteins reveals widespread existence of a beta-bulge formed at the beginning of strand a and the end of strand b, termed as WD(b–a) bulge: among a total of 259 WD40 blades, there are 243 such β-bulges. The R(1) positions in these WD(b–a...

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Autori principali: Wu, Xian-Hui, Wang, Yang, Zhuo, Zhu, Jiang, Fan, Wu, Yun-Dong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419727/
https://ncbi.nlm.nih.gov/pubmed/22916195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043005
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