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Discovery of NSAID and anticancer drugs enhancing reprogramming and iPS cell generation

Recent breakthroughs in creating induced pluripotent stem cells (iPSCs) provide alternative means to obtain ES-like cells without destroying embryos by introducing four reprogramming factors (Oct3/4, Sox2, and Klf4/c-Myc or Nanog/ Lin28) into somatic cells. iPSCs are versatile tools for investigatin...

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Detalhes bibliográficos
Main Authors: Yang, Chao-Shun, Lopez, Claudia G., Rana, Tariq M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419601/
https://ncbi.nlm.nih.gov/pubmed/21898684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.717
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