An exploratory analysis on gene-environment interactions for Parkinson disease

Little is known about gene-environment interactions in Parkinson disease (PD). We examined potential interactions of smoking and caffeine intake with ten GWAS SNPs at or near the SNCA, MAPT, LRRK2 and HLA loci among 584 PD patients and 1,571 controls. The main effects of these SNPs and environmental...

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Main Authors: Gao, Jianjun, Nalls, Michael A, Shi, Min, Joubert, Bonnie R, Hernandez, Dena G, Huang, Xuemei, Hollenbeck, Albert, Singleton, Andrew B, Chen, Honglei
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419385/
https://ncbi.nlm.nih.gov/pubmed/22763023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2012.06.007
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