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Prevention of lung injury by Muc1 mucin in a mouse model of repetitive Pseudomonas aeruginosa infection

OBJECTIVE AND DESIGN: To determine whether repetitive airway Pseudomonas aeruginosa (Pa) infection results in lung inflammation and injury and, if so, whether these responses are affected by Muc1 mucin. Muc1 wild type (WT) and knockout (KO) mice were compared for body weights, lung inflammatory resp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Umehara, Tsuyoshi, Kato, Kosuke, Park, Yong Sung, Lillehoj, Erik P., Kawauchi, Hideyuki, Kim, Kwang Chul
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419284/
https://ncbi.nlm.nih.gov/pubmed/22643830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00011-012-0494-y
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