Lenalidomide, cyclophosphamide, and dexamethasone (CRd) for light-chain amyloidosis: long-term results from a phase 2 trial

Light-chain (AL) amyloidosis remains incurable despite recent therapeutic advances. Given the activity of the lenalidomide-alkylating agent combination in myeloma, we designed this phase 2 trial of lenalidomide, cyclophosphamide, and dexamethasone in AL amyloidosis. Thirty-five patients, including 2...

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Detalhes bibliográficos
Main Authors: Kumar, Shaji K., Hayman, Suzanne R., Buadi, Francis K., Roy, Vivek, Lacy, Martha Q., Gertz, Morie A., Allred, Jacob, Laumann, Kristina M., Bergsagel, Leif P., Dingli, David, Mikhael, Joseph R., Reeder, Craig B., Stewart, A. Keith, Zeldenrust, Steven R., Greipp, Philip R., Lust, John A., Fonseca, Rafael, Russell, Stephen J., Rajkumar, S. Vincent, Dispenzieri, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418771/
https://ncbi.nlm.nih.gov/pubmed/22504925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-407791
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