The Meningococcal Minor Pilin PilX Is Responsible for Type IV Pilus Conformational Changes Associated with Signaling to Endothelial Cells

Neisseria meningitidis crosses the blood-brain barrier (BBB) following the activation of the β2-adrenergic receptor by the type IV pili (TFP). Two components of the type IV pili recruit the β2-adrenergic receptor, the major pilin PilE and the minor pilin PilV. Here, we report that a strain deleted o...

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Detalhes bibliográficos
Main Authors: Brissac, Terry, Mikaty, Guillain, Duménil, Guillaume, Coureuil, Mathieu, Nassif, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418752/
https://ncbi.nlm.nih.gov/pubmed/22778100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00369-12
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